News in Adjuvant Th erapy of Non-seminomatous Germ Cell Testicular Tumors of Stage I
نویسندگان
چکیده
منابع مشابه
Differential Akt signalling in non-seminomatous testicular germ cell tumors.
AIM To investigate the protein kinase B (Akt) signalling proteins phosphatase and tensin homolog (PTEN), phosphorylated-Akt (p-Akt) and cyclin-dependent kinase inhibitor 1B (p27(Kip1)) in non-seminomatous germ cell tumors (NST) with a view to future investigative approaches. MATERIALS AND METHODS The expressions of PTEN, p-Akt and p27(Kip1) were immunohistochemically assessed in 17 teratomas,...
متن کاملThe management of low-stage non-seminomatous germ cell tumors
The prognosis of patients with stage I non-seminomatous germ cell tumors is in general very good. However, a large number of patients relapse with metastatic disease after orchidectomy Therefore, adjuvant treatment, in the form of either chemotherapy or retroperitoneal dissection is recommended, although active surveillance has been found to be as good a way of treating these patients with over...
متن کاملIsolated eyeball metastasis of non-seminomatous germ cell testicular tumor.
INTRODUCTION Testicular tumors most frequently metastasize to regional lymph nodes. Non-seminomatous tumor metastasis of testicle (NSGCTT) to the eyeball is rare. CASE REPORT We presented a 24-year old man, referred to the ophthalmologist due to acute pain and abrupt loss of sight in the left eye accompanied by its enlargement. Orbital and endocranial computerized tomography (CT) was carried ...
متن کاملIs modified retroperitoneal lymph node dissection alive for clinical stage I non-seminomatous germ cell testicular tumor?
PURPOSE To evaluate efficacy of modified retroperitoneal lymph node dissection (RPLND) in the management of patients with pathological stage (PS) I non-seminomatous germ cell testicular tumor (NSGCT) in a retrospective study. MATERIALS AND METHODS Between April 2002 and April 2012, 55 patients with clinical stage (CS) I NSGCT had undergone modified RPLND according to Sloan-Kettering modified ...
متن کاملgenetics of testicular germ cell tumors
testicular germ cell tumor (tgct) is the most solid tumor in 20-40 years old man. tgct account for 95% of testicular tumors and represent a unique type of human cancer from several different perspectives. tgct arise by transformation of germ cells. the transformed germ cells exhibit ploripotentially to differentiate into embryonic. extra-embryonic, and somatic tissue types, and are highly sensi...
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ژورنال
عنوان ژورنال: Klinicka onkologie
سال: 2016
ISSN: 0862-495X,1802-5307
DOI: 10.14735/amko2016107